45. The operational rate of the Krebs cycle (TCA cycle) is strictly regulated by the cellular energy and redox states. Which of the following enzymes is considered the most critical rate-limiting step in the cycle, being allosterically inhibited by high concentrations of ATP and NADH, and significantly activated by ADP?
(A) Citrate synthase
(B) α-ketoglutarate dehydrogenase complex
(C) Isocitrate dehydrogenase
(D) Succinate dehydrogenase

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統計： A(0), B(1), C(4), D(1), E(0) #3839980

詳解 (共 1 筆)

#7318555

TCA Cycle 的三大關卡：

  1. Citrate synthase 

  2. Isocitrate dehydrogenase 

  3. $\alpha$-ketoglutarate dehydrogenase 

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