69. Peptidyltransferase catalyzes the formation of the peptide bond. According to the structural analysis mentioned in the text, how does this catalysis occur?
(A) A conserved AMP residue in the 23S rRNA abstracts a proton from the amino group of the A-site aminoacyl-tRNA, making it a better nucleophile.
(B) The reaction requires the hydrolysis of at least four ATP molecules to activate the carboxyl group of the C-terminal amino acid.
(C) A protein subunit within the 50S ribosome acts as a general acid-base catalyst to stabilize the tetrahedral intermediate.
(D) The attacking nucleophile in the formation of a peptide bond is a water molecule provided by the surrounding cytoplasm.
(E) Peptide bond formation occurs by transferring the growing polypeptide chain from the P-site tRNA to the aminoacyl-tRNA in the A site.